Can a compound protect DNA from oxidizing agent in DNA protection assay ?
and same compound having anticancer potential can cause DNA damage in cancer cell line ?
António Maximiano Fernandes
Thousands studies showed that antioxidante agents protect cells from oxidative stress by scavenging free radical. Eg: Polyphenols from plant. But didn't got you point about damage in cancer cell line.
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Yogesh Kumar
@Antonio
I mean to say if a compound is anticancer, it induces apoptosis that cause DNA fragmentation (stained by DAPI ) in cancer cell lines.
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