Based on the similarities between Hepatitis B and Hepatocellular carcinoma, what's the probability that a drug developed to effectively rid the body of Hepatitis B could be effectively used to manage HCC caused by hepatitis B virus
Clearance of serum HBV DNA and lowering HbsAg level by taking antiviral drug significantly reduce risk of developing HCC. Chiang et al had demonstrated a strong decline of HCC following antiviral treatment as the lifetime risk of developing HCC was as high as 21%.
By using antiviral drugs in those with hepatitis b induced HCC, overall survival rate of HBV-related HCC after curative and palliative therapies, are proven to be improved. This could be explained by antiviral drug which could reduce the viral load/HBsAg level, with improving liver function, reducing or delaying HCC recurrence. And this is already applied in some national treatment guidelines/consensus of hepatitis B induced HCC.
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