Hi,

if you want to compare multiple genomes in order to investigate similarity between your strain and others, (genes unique, genes shared between all or just shared with some other individuals) you can use OrthoMCL (http://orthomcl.org/orthomcl/). Using whole proteins of each individuals you want to compare, OrthoMCL use a blast approach (all versus all) and then generate clusters you can use to draw a Venn diagram. Typically, plot more than 5-6 individuals in a Venn results in graph not so easy to understand.

I hope it helps.

Regards

Use http://www.biovenn.nl.

Publication: Article Hulsen T, de Vlieg J, Alkema W.. BioVenn-a web application f...

you can use this online tool DiVenn which will generate a nice graph (https://divenn.tch.harvard.edu)