Can the mitochondrial DNA replication be labelled with EdU or BrdU?
In this publication detection of both nuclear and mitochondrial DNA by BrdU labeling is described:
http://www.ncbi.nlm.nih.gov/pubmed/23300711
I hope this information helps you.
Best regards, Christian
thanks a lot Christian Q. Scheckhuber :)
Right, but do careful controls - incorporation may also be due to mtDNA repair, not replication.
@rudolf j wiesner: thanks for suggestion. may i know how to set controls for determining, labelling is due to replication or repair ?
thanks :)
I suggest to read some papers where people have used this method!
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