I am using HDOCK to perform molecular docking, but HDOCK has a limit of 500 nucleotides for the receptor. However, we want to perform docking on the entire 3' UTR region. Can anyone suggest a solution to this problem?
Yes, We can Perform Molecular Docking of these molecules using Autodock
You can use FastDRH server for docking in easy way and MMPBSAGBSA also available there.
While AutoDock is primarily designed for protein-ligand docking, it's not the ideal tool for docking microRNA (miRNA) and mRNA.
Do check out this article (https://www.biorxiv.org/content/10.1101/2023.07.28.551063v3)
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