Can someone suggest a protein majorly involved in the cancer pathway of breast cancer that can be used as a better in silico target?

More Servin Wesley's questions See All

Does anyone know the physiological activation of uPA (urokinase plasminogen activator)?

And how PAI 1 is related to the increased metastasis in human cancers? Detailed answers appreciated.

04 May 2013 5,344 4 View

Oxidation of isolated Phytocompound in column chromatographic elution...?

Is there any chance for oxidation of an isolated plant compound, eluted in column chromatography? Since the fraction (containing solvent and compound) is separated by condensation- distillation...

09 October 2012 3,505 27 View

Will a plant callus show an increase in secondary metabolite production after Agrobacterium tumefaciens infection?

Does the size of the callus after infection increase the quantity of secondary metabolite?(Infection with Ti plasmid without a gene of interest)

09 October 2012 8,125 9 View

List of in vitro free radical scavenging assays with same reaction substrates. (Substrate specific)

Can anyone list the in vitro radical scavenging assays with same substrates (involved in the reaction) so that i can avoid those non-substrate specific assays?

08 September 2012 2,860 1 View

Why have my successive solvent plant extracts (from non-polar to polar) not showed similar results in different in vitro free radical scavenging assays?

I am having difficulty in interpreting the results because each extract is superior to one another in some specific assays and not in other assays.

08 September 2012 3,850 8 View

List of in vitro free radical scavenging assays with same reaction substrates.

can any one list the in vitro radical scavenging assays with same substrates (involve in the reaction) .... so that i can avoid those assays. Thanks.

08 September 2012 8,027 0 View

Is it necessary to do all the proposed in vitro free radical scavenging assays (for plant extracts) even though they are substrate specific?

Can the repetition of assays of same substrates be avoided?

08 September 2012 1,463 7 View

Are there instances where molecules with larger molecular weights exhibit greater mobility than those with smaller molecular weights?

Hi, I know that low molecular weight (MW) molecules generally tend to have higher mobility, while high molecular weight molecules tend to have lower mobility. However, in my experimental...

06 August 2024 1,495 2 View

Weak DAPI staining after immunohistochemistry - how to improve?

After immunohistochemistry of previously fixed in PFA and EtOH and then frozen 20 μm sections of zebrafish brain, DAPI staining is very weak (right) compared to the same sections stained without...

05 August 2024 9,637 2 View

The Curse of Evolution and Complexity?

Brain and body mass together are positively correlated with lifespan (Hofman 1993). The duration of neural development is one of the best predictors of brain size, and conception is the best...

05 August 2024 6,247 3 View

For an in-vitro drug release study, what molecular weight cut-off (MWCO) dialysis bag is required for a 117 kDa protein?

kindly reply me. Thanking you in advance.

05 August 2024 7,727 4 View

How to start a Molecular Dynamics Simulation?

Is it possible to conduct a molecular dynamics simulation to see the effects of a specific carbohydrate on the structure of lipids (e.g., micelle structure)? I am a beginner in this field and plan...

03 August 2024 3,371 3 View

Radiogenomics Cancer Research Challenges?

what are the top 3 challenges to the advancement of the field of Radiogenomics in cancer research? is it the availability of easily available low-cost matched imaging and biosamples with clinical...

03 August 2024 5,828 4 View

Which will be the best software for the Hydration shell analysis with molecular dynamics?

I am using a windows system, what software I should use for hydration shell analysis with molecular dynamics?

02 August 2024 3,143 4 View

Can anyone provide me with molecular docking softwares/ websites?

Molecular docking software/ websites?

02 August 2024 8,704 7 View

How to restart MD without using checkpint file in GROMACS?

Dear All Gromacs User I would like to restart MD without using checkpint .cpt files? I heard there is a way for acheiveing this. Any input and sugegstions are most welcome. Thanking You Budheswar

29 July 2024 3,084 8 View

I am working on my Master's thesis on the biogeography of the genus Ruagea and I would like to ask, could someone help me to check whether my result?

I created a file with my outgroup and ingroup species using Beauti, ran it in BEAST, viewed it in Tracer, and then used TreeAnnotator to create a file that I imported into RASP. Could someone...

28 July 2024 2,979 1 View