From my understanding, proteins in the blood have distinct charges as they move through the bloodstream. If a protein had a sufficiently, say positive charge, and a negative charge was applied outside the bloodstream on the skin, would it cause that positively charged protein to accumulate near that location on the body? I am unaware of any current research on this topic and would be very grateful if anyone could point me to some.
One potential issue I see with this is if charged proteins are balanced by counterions in vivo and if this may prevent the process from working.