Greetings, I'm trying some new homogenization protocols and I've realized we don't have Sodium pyrophosphate (Na4P2O7). It's a endogenous phosphatase inhibitor and I was tinking, can It be replaced with Disodium phosphate (Na2HPO4)?

I'm pasting the buffer compounds below:

in mM

Tris, 65.2;

NaCl, 150;

EDTA, 2;

NaH2PO4, 50;

Na4P2O7, 10;

pH 7.4 containing 0.1% SDS, 0.5% deoxycholate, 20% protease inhibitor cocktail

I'll be more gradefull for an advice!