I am from IICB kolkata and working on cell cycle regulation in glioblastoma multiforme (GBM).
its wild type but its affector PTEN is mutated,which results in constitutive activation of akt protein.
thanks for your reply. but according to the ATCC PTEN is WT in LN229 cell line.
thanks making me more clear,
If u are keenly interested in this ,go directly for Targeted Exome Sequencing of pi3k gene in LN229 cell line , further validate it .this can provide u clear and reliable ans.
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