Does any one has information OR used NIK inhibitor that is commercially available?
As well as TRAF activators too?
If some one already used please recommend me too as well their working doses
Thank you!
4H-isoquinoline-1,3-dione and 2,7-naphthydrine-1,3,6,8-tetrone are reported to inhibit NF-kB inducing kinase inhibitor.
Ref.
Bioorg Med Chem Lett. 2010 Aug 1;20(15):4515-20. doi: 10.1016/j.bmcl.2010.06.027. Epub 2010 Jun 8.
NF-kappaB inducing kinase (NIK) inhibitors: identification of new scaffolds using virtual screening.
Thank you Respected Go J Yoshida , as I checked even before here in this article they claimed about 50 percent inhibition, I wonder if any latest more efficient inhibitor available commercially. NIK SM1 is also common but having some off-target effects.
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