Can anyone please explain the role of miRNAs during type-2 diabetic condition?

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Vishal Sarsani

Mayilvanan,

Many recent studies show that expression of microRNAs can affect insulin secretion which is related to type-2 diabetes

Please look into following papers :

http://diabetes.diabetesjournals.org/content/60/7/1825.full

http://www.ncbi.nlm.nih.gov/pubmed/21118127

Mojtaba Parvizi

Many effect could be discussed here. Effect on insulin, vessels ans etc. It is depend on your research area and focuses.

Mayilvanan Chinnaiyan

Ya right now I am working in high fat diet induced insulin resistance, on which I would like to know the miRNA aspects in glucose homeostasis in skeletal muscle and adipogenesis regulation. Any one, can you help me in that aspects.