Hello all-

I am looking for is some sort of evidence/research to show that various methods for isolating botanical molecules (lets say nicotine, caffeine, cannabinoids etc) produce comparable/identical products, even though the method of extraction and/or isolation may differ.

There are several methods, but the general consensus from what I hear is that the end isolated molecule is the same no matter the method of isolation (eg: CO2 extraction versus isopropyl alcohol extraction). I am having a heck of a time finding scientific literature that has actually compared and characterized isolates of the same molecule using different methods and found them to be the same identical molecules.

Yes, I know, a molecule is a molecule no matter the source, but I am finding this to be an assumption. Maybe I am missing some older, or basic tried and true references, but I am also not a chemist, so this is sort of toeing the line of what is in my wheelhouse.

I would really appreciate any and all help to finding resources. Thanks in advance