Unfortunately, there is no specific treatment of osteogenesis imperfecta. You may try oral or intravenous biphosphonates to increase bone density. In case of long bone deformations or/and fractures, intramedullary nailing is indicated.

Thanks a lot Panayot for your answer. Best regards.

Dear Faiq,

all the children we treat with OI have portacaths inserted after diagnosis and regular biphosphonate infusions to try and strengthen their bones.

Thanks a lot Roy for your answer. Best regards.

Dingos homages are a good options in order to decrease the number of fracture in Oi patients but not when the fracture has happened and when you operate it because the drug interfere with the healing process 

Thanks a lot Antonio fro your answer.

Intravenous bisphosphonate therapy is the right treatment. For treatment monitoring, be guided by fracture rate, mobility, pain, bone density (DXA, if you have) and change in vertebral shape (you would hope for re-shaping during therapy). Is there a family history of OI? If not, worth exploring genetics.

Thanks a lot Wolfgang for your answer.Best regards

Infusion of bisphosphonates at regular intervals according to protocols accepted across multidisciplinary.

Prevention of deformities and treatment of fractures. Often the deformities caused by fractures and fractures occur at the level of deformity.

Telescopic nails are the gold standard.

In very young children or very severe forms they can be used single or nails with nail sliding technique (ten or rush).

Second Protocol discontinuing drug treatment for 4 months after surgery.

Profits can be pulsed magnetic fields (PEMFs).

Enjoy. P

Thanks a lot Pietro. Best regards.

Any update on this patient care ?

http://www.oif.org/site/DocServer/_Adults__Adult_Fracture_and_Care.pdf?docID=7184

Bisphosphonates (iv) therapy is commonly used for patients with Osteogenesis Imperfecta (OI). However, OI expresses itself in different range of severity and some forms of OI type ii have a high perinatal morbidity and mortality rates.