Effect of hemodialysis on blood viscosity, blood flow rate, heart rate, and blood pressure.
Patients on hemodialysis have increased viscosity, that is multifactorial and can contribute to increased cardiovascular mortality in this group of patients with end stage renal disease (1).
Blood flow rate (BFR) through dialysis machine is one of the parameter of effective hemodialysis, and BFR 250 ml/min is associated with less effective dialysis, tissue ischemia, particularly the heart, and can lead to increased vascular events (2).
Dialysis is considered one of the strongest antihypertensive in patients who are undergoing hemodialysis. This why in hypertensive patients, antihypertensive drugs on the day of dialysis should not be given before dialysis session, because patients often develop hypotension during dialysis. Associated with hypotension, most of such patients develop tachycardia, but others have no effect, while a few may develop bradycardia(3). Hypotension is particularly more common in patients with ischemic heart disease and patients with diabetic complications (particularly autonomic neuropathy) with renal failure (4)
1. Article Whole blood viscosity: Effect of hemodialysis treatment and ...
2. Article The impact of blood flow rate during hemodialysis on all-cau...
3. Article The heart rate response pattern to dialysis hypotension in h...
4. Article The influence of autonomic neuropathy on hypotension during dialysis