Thanks, dear Abhijeet... While I'm looking for the reasons behind Dolly's death I found that In 2013, it was shown through mice that the nuclei didn’t age irreversibly.
If you are just finding out the reason of dolly's death, she died of lung cancer and Roslind institute's investigation did not pointed towards any possibility of dolly's death just due to she was a clone. Lung cancer of that particular type is very common in sheep.
Nevertheless, if you have some information regarding reversible aging, you can share your source and knowledge.
Several experimental evidences showing that an adult somatic nucleus implanted into an enucleated oocyte can give rise to a whole new individual strongly suggests that the integrity of the genome of an adult nucleus is fully preserved. Recent experimental evidence showed that pluripotency gene-based cell reprogramming can erase the epigenetic marks of aging and rejuvenate cells from old individuals reversing most signs of aging and that when induced pluripotent stem cells are differentiated back to the cell type of origin, the rejuvenated cells share many of the features of wild-type counterparts from young donors.
Reference:
Article The Emerging View of Aging as a Reversible Epigenetic Process
Regards.
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