Silver nanoparticles are currently effective against multiple antibiotic resistant bacteria.
Silver nanoparticles which biosynthesized by bacteria are high effective specially against MDR pathogenic bacteria.
Silver nanoparticles are effective against antibiotic resistant bacteria. The silver nanoparticles synthesized biologically or chemically can be equal in their effectiveness. The only point of concern in the use of these nanoparticles is their non selective toxicity in some cases, leaving behind a safety concern for considerations. Some schools of thought have recommended the use of silver nanoparticles especially in treating difficult-to-treat and highly virulent pathogens classified with critical criteria by WHO (2017) for R and D.
My understanding of the question is: 'can bacteria form resistance to nano particles?' I will say yes. When such particles are administered sub-therapeutically, it may elicit some level of resistance.
Of course bacteria will develop resistance to silver just like any other biocides, and it has been described in literature. The sil-family genes have also been found on plasmids with other antibiotic resistance genes, so co-selection is also an issue (i.e. using silver may also lead to spread of antibiotic resistance).
microbial resistance susceptible to silver nanoparticles. Silver nanoparticles synthesized biologically physically or chemically can be equal in their effectiveness.
Bacterial resistance to silver, copper, and zinc nanoparticles has been highlighted in both Gram-negative and Gram-positive bacteria isolated from inert surfaces, soil, or the intestinal contents of animals fed with zinc and copper supplements
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