Any issues with antibody production in ExpiCHO cells?

16 April 2019 0 7K Report

Recently, we started using ExpiCHO cells for production of recombinant monoclonal antibodies. New batches made in ExpiCHO seems to have different properties than old ones made in 293e cells. When used in Western Blot, they give higher background and lack specificity.

Does anybody experience similar issues with ExpiCHO cells?

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