The scientific study of the nervous system | Contact experts in Neuroscience to get answers
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Questions related to Neuroscience
How long after the conditioning (control) rats remember the shock. I know it depends on various factors (age of the animal, shock mA, etc.). What's the longest period you've come upon. Thanks
10 October 2019 9,566 3 View
I want to test the effect of a neuroprotective drug on rotenone rat model of Parkinson's disease but after reading the related articles about my work, I became doubts about select the best dosage...
10 October 2019 10,010 4 View
We are looking to inject optogenetic contructs with ArchT or eNpHR3.0 in ACC and we are considering several options. We are curious what is your experience with the different AAV serotypes,...
10 October 2019 3,304 1 View
I'm working with expansion microscopy and I need my samples to have high stability (esp. thermostability) due to intense light beams that are involved in my application. As such, I am trying to...
10 October 2019 7,366 4 View
I am trying to characterise GABA developmental switch in iPSC derived neurons using Ca2+ imaging. However, as I add GABA agonist, I observe the spontaneous activity of several neurons being...
09 September 2019 870 2 View
I have two strains of animals and three different treatments on each strain (2 strains X 3 treatment). One of the strain (strain 1) was used as control, and the experiment was to test whether...
13 August 2019 3,936 2 View
In article below, the figure 4 (page 8) shows a diagram in which the correlation between EEG and d2 test is plotted. I couldn't find any sources describing how to plot d2 results. May anybody help...
08 August 2019 10,086 6 View
I am looking for visual stimuli that produce a similar effect than the well know “Dalmatian dog illusion” (see Figure attached). If you look briefly at the Dalmatian dog illusion for the first...
08 August 2019 7,557 3 View
04 August 2019 7,914 6 View
I need to device an experiment with the n-Back Pointing task without any hardware complement; e.g., no tablet to execute the reaching movements or computer touch screen to select the presumed...
07 July 2019 986 1 View
I am doing a stain for myelin using Eriochrome Cyanine (Solochrome Cyanine). The counterstain is a neurofilament stain visualized using DAB. I am working from 45 micron sections of brain tissue....
07 July 2019 6,140 1 View
I am looking for any good protocol for dissociation of single hippocampal neurons from adult mice. We'll perform flow cytometry and eventually work on qPCR. As our lab is not specialized for...
07 July 2019 8,447 2 View
Hi. I am a graduate student using Doric Neuroscience Studio. Since there seems to be not much references about using Doric's fiber photometry console(FPC) (v. 4.x or 5.0.0) and our lab doesn't...
28 June 2019 9,726 2 View
I have always understood an allosteric site to be a regulatory site on an enzyme that is separate from the active site of catalysis, but I have never heard that the allosteric site MUST be on a...
27 June 2019 761 4 View
I am working with an extremely unbalanced dataset with a total of 44 samples for my research project. It is a binary classification problem with 3/44 samples of the minority class for which I am...
13 June 2019 9,446 4 View
Hi, I want to investigate if there are significant differences in the difference of two groups. I have two populations and both populations have a control group and a experiment group. To...
13 June 2019 615 7 View
I routinely functionally assess the iPSC derived neurons using calcium imaging with Fluo-4/AM (490nm/510nm). However, have not been successful at using those same neuronal dishes for carrying out...
06 June 2019 3,654 2 View
Are there any freely available Local Field Potential (LFP) datasets available, especially recorded during motor actions?
06 June 2019 2,432 6 View
I apply a detrended fluctuation analysis (DFA) to rs-fMRI signal before and after some task. Certain areas show an increase in Hurst exponent in after-task activity in comparison to the initial...
26 May 2019 9,060 3 View
hi, so i have a question with regards to clinical significance, statistiscal significance and effect size (ES). rigth now m doing e literature on the effect of physiotherapeutic intervention to...
25 May 2019 847 0 View
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06 May 2019 5,478 4 View
Dear all, For the analysis of intracranial electrophysiological recording in animals, some tutorials montion that the analysis should be used for stationary signal, so there should be some...
05 May 2019 587 12 View
I would be thankful if you name some references
05 May 2019 9,550 1 View
I would be thankful if you recommend me some refrences about it
05 May 2019 9,149 1 View