Why LTD is necessary in hippocampus? What purpose does it serve there?

05 May 2019 1 9K Report

I would be thankful if you recommend me some refrences about it

1. Dong, Z., Gong, B., Li, H., Bai, Y., Wu, X., Huang, Y., ... & Wang, Y. T. (2012). Mechanisms of hippocampal long-term depression are required for memory enhancement by novelty exploration. Journal of Neuroscience, 32(35), 11980-11990.

2. Ge, Y., Dong, Z., Bagot, R. C., Howland, J. G., Phillips, A. G., Wong, T. P., & Wang, Y. T. (2010). Hippocampal long-term depression is required for the consolidation of spatial memory. Proceedings of the National Academy of Sciences, 107(38), 16697-16702.

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