Cancer

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Questions related to Cancer

Do chalcones have selectivity towards any particular enzyme?

I am interested in chalcones and their activities. I am amazed  with their therapeutic potential but really got a doubt whether they have  selectivity  towards any particular target?

28 June 2017 2,424 1 View

How biochemistry of Caffeine is associated with the cancers, as most of the studies shows the preventive role of it in cancer

How caffeine is associated with Cancers

19 June 2017 1,461 1 View

Nichotherapy for cancer. Is metformin suitable agent?

Metformin's anti-cancerous properties have been demonstrated in various cancer cells in vitro, such as lung, pancreatic, colon, ovarian, breast, prostate, renal cancer cells, melanoma, and even in...

17 June 2017 4,975 3 View

Can someone help me with static anode x-ray tube spectra?

I need to perform Monte Carlo simulations of a imaging device (dental) with static anode x-ray tube.  Can you provide me one or point out a reference/paper/article? Thanks in advance!

05 June 2017 7,007 8 View

Do mouse embryonic fibroblasts express pluripotency markers?

Hello, I am doing flow cytometry to evaluate the pluripotency of mouse embryonic stem cells (mESCs) which have been derived and cultured on mouse embryonic fibroblasts (MEFs) Unfortunately, I am...

01 June 2017 2,427 4 View

WHAT best method for induce cancer in prostate of Rat?and how long time for induction cacner in prostate of Rat

exercise and prostate cancer in animal model, and how long time for induction cacner in prostate of Rat

25 May 2017 1,440 3 View

Is there an RNA-seq database on cancers that includes patient's county/general location?

I am looking for something like NCI's TCGA databases (with patient county / area). I know any private / personal identifying information is removed but if anyone has an idea, please let me...

22 May 2017 1,389 0 View

When to obtain the blood/ CSF sample for better research management in patients with precatamenial epilepsy?

We investigated hormonal pathophysiology and water retention as the major factors in catamenial epilepsy. When is the best to obtain the blood/ CSF sample for better research management in...

16 May 2017 301 1 View

Is it publication available to investigate a gene in cancer to find its relation with some known and important genes in the cancer using IHC?

If a new gene had been reported to be an oncogene, and it correlated with chemotherapy resistance, migration, proliferation, apoptosis in the cancer,to learn more about the mechanism of the gene....

11 May 2017 9,355 2 View

How to analyze synonymous mutations?

Hi everyone, I'd like to analyze some synonymous mutations by using different predictors. I'm wondering what are the best predictors or whether there are any good publications focusing on this...

10 May 2017 1,693 1 View

Are you aware that of the TRISST trail - which is looking at this also in Seminoma?

http://www.ctu.mrc.ac.uk/our_research/research_areas/cancer/studies/trisst_mrc_te24/ Over 600 patients have been recruited so far - with MRI scans

04 May 2017 4,880 3 View

Effect of albumin?

What is the burning effect on albumin and how explain to me if anyone knows or help me with articles on this? And how to manage this problem guide this?

03 May 2017 2,901 1 View

Anyone working with mouse embryonic stem cells?

My mouse embryonic stem cell line are not working. They are not able to attach to the surface of coated dishes ( I have tried both Geltrex and 0.5% gelatin) remain in suspension. I am using ESGRO...

28 April 2017 7,709 12 View

I can visualize a strong protein band in SDS gel but cant get any peak at 280nm on nanodrop?

The sample buffer has 500mM of imidazole.

24 April 2017 4,236 7 View

Hypodopaminergic vs hyperdopaminergic hypothesis of ADHD?

Methylphenidate (Ritalin), the first-line drug for treating ADHD, works by increasing dopamine, however the animal-models for ADHD are hyperdopaminergic rats/mice. How can we explain this?

22 April 2017 2,861 1 View

What are effective treatment protocols for adults with nonfluent-variant PPA?

Am looking for treatment recommendations for clients with nonfluent variant-PPA. Thank you in advance! 

20 April 2017 4,766 0 View

Can be anti-tumor compound have no cytotoxic activity?

I have tested a plant extract for cytotoxic activity against cell lines and it showed potent activity? The pure major isolated compounds have high values for IC50% and  its amount is very small to...

15 April 2017 9,182 6 View

My ligand bind with phosphate that is present in receptor protein but only with mutated one not with the normal one how can i justify these results?

please help me I am working on mutate and normal protein in comparison. I do docking of both proteins with compounds. The compound shows binding to phosphate of mutated structure and the same...

15 April 2017 6,965 4 View

Is it possible that case series study contain control group ,but there are no intervention or investigation were done for both,just a history ?

I want to know your opinions in the study design of this article. thank you very much 

12 April 2017 7,018 2 View

Can I get your help to chose good parameters in my project?

I want to work on Anabolic androgen steroid Dianabol  but most of parameters are studded by other researchers like blood profile and hormones or liver enzymes.. I think to study more specific...

10 April 2017 1,538 6 View

How do you proppose to do that?

The matrix is both a complex structure and an energy field associated with it. Psychiatric syndromes could be a result of changes in this energy field. How do you proppose to tackle that?

06 April 2017 7,283 1 View

Using PROC GENMOD in SAS for Poisson Regression. How to obtain predicted counts?

If you use proc genmod for a Poisson Regression for predicting (say) cancer counts from poverty rate, and then we use as the offset the natural log of the population, what exactly is obtained as...

04 April 2017 8,835 1 View

Lung metastasis animal model?

I am looking for Lung metastatic model for C57B6J mice. We inject LLC or B16F10 tail vein for experimental metastasis, but i want a model that tumor cell lines implanted in subcutaneous or...

27 March 2017 1,228 2 View

Nilotinib in Alzheimer disease?

There is someone interested about the effect of nilotinib in Alzheimer disease?

17 March 2017 5,543 5 View

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