Jananishree Sathiyamoorthy

12 Questions 3 Answers 0 Followers

Questions related from Jananishree Sathiyamoorthy

How to increase zetapotential of a PVA based formulation?

The PVA and drug was synthesized using solvent evaporation and nanoprecipitation. In this method, the drug was solubilized in ethyl acetate. The PVA was dispersed in water. Under constant stirring...

02 June 2025 5,772 1 View

Which is a best tool for HPLC simulation software?

I am trying my own lab synthesized compound in HPLC but facing difficulties and then I came to know that there are certain simulation softwares that helps to design the sensitive method to be used...

20 January 2025 2,593 3 View

I have used PVA to solubilize my drug by using solvent evaporation nanoprecipitation method. Can i say it as a nonoformulated compound?

I have a poorly soluble drug. I used PVA 3% to dissolve my drug by solvent evaporation nanoprecipitation and the size of the particles came around 300nm. May i now consider it as a nanoparticle

17 January 2025 8,549 0 View

I have a drug of poor solubility, may i use PEG4000 for the solubilization of drug to be given via IV. If can be give how much % can be used?

My drug is poorly soluble in DMSO. I tried 1%PEG4000 and it is dissolving, but i have doubt whether i can use it for IV. Because PEG4000 is a high molecular weight compond

08 January 2025 2,651 3 View

Can I use PVA to dissolve my drug for IV formulation?

I have a drug of poor solubility, may i use PVA for the solubilization of drug to be given via IV. If can be give how much % can be used?

07 January 2025 3,395 3 View

For the PK study how to process the blood sample- plasma isolation and detection of drug using HPLC?

For the PK study in an animal model, how to process the blood sample for plasma isolation and deproteinization for detecting the drug in HPLC

28 September 2024 3,525 1 View

I need to use 0.005%EDTA for reverse phase HPLC. how to prepare?

I have seen 2 different EDTAs: one is free acid, and the other is disodium salt. Along with EDTA, I am using methanol and acetonitrile. Now how to prepare EDTA as EDTA doesn't dissolve in water as...

25 September 2024 600 1 View

Is still the cryptococcus sp. considered as the top most critical priority pathogen?

In the year 2022 the WHO released a fungal priority pathogen list in which Cryptococcus neoformans being placed at the top most of critical priority pathogen. Is it still a threat to human...

11 June 2024 4,099 3 View

How to seperate the formed NLC from the aqueous solution?

I have done the NLC formulation using ultrasonication and microemulsion techniques. Now I have the whole emulsion as a milky white liquid. How to separate the NLC from the aqueous solution. I have...

12 February 2024 3,372 3 View

How to prepare 0.84% w/w tween 80 aqueous hydrophilic solution?

how to calculate w/w%

23 January 2024 9,656 1 View

How will the Nanostructured lipid carrier appear at the end of the formulation?

I am new to Nanoformulations. I have done the synthesis of NLC for an antifungal compound using the protocol published in Improved yeast delivery of fluconazole with a nanostructured... At the end...

22 September 2023 8,756 1 View

Why a combination of hydrophobic and hydrophilic polymer is used for hydrophobic drug formulation?

For hydrophilic drugs only hydrophilic polymers are used. Then why a combination of hydrophilic and hydrophobic polymers are used for hydrophobic drugs

07 August 2023 9,942 3 View