The PVA and drug was synthesized using solvent evaporation and nanoprecipitation. In this method, the drug was solubilized in ethyl acetate. The PVA was dispersed in water. Under constant stirring and application of heat, the PVA was solubilized in water. After complete dissolution of PVA in water, the drug dissolved in ethyl acetate was added to the PVA mixture drop by drop under continuous stirring. Once the drug dissolved ethyl acetate was completely dropped in the PVA mixture, and the mixture was further stirred for at least an hour for complete evaporation of ethyl acetate. The PVA i am using is High molecular weight