Statistical methods for comparing gene expression curves?

Hi all, I have generated two gene expression curves by measuring bioluminescence every 10 mins for 12 hrs. These curves tend to overlap at at some time points, while a difference can be seen at...

02 February 2021 2,613 7 View

Which is Suitable machine learning algorithm for weak data (small dataset)?

I have a small dataset. Which machine learning algorithm is suitable for this?

07 January 2021 7,833 8 View

How to convert the pixels into inches in matlab?

i have found the area of segmented image in pixels. How can i convert into inches

01 January 2021 3,336 7 View

How to calculate the area of segment of binary image array in mat lab ?

We have segmented a part from grey scale image using image segmenter (app in mat lab ) and stored as matlab structure. from that structure , how can we calculate the area of the segmented part...

24 December 2020 4,040 3 View

What is the current status on regulatory approvals of COVID-19 vaccines?

What is the current status on regulatory approvals of vaccines meant for COVID-19 according to USFDA, EMA, TGA, etc?

10 June 2020 7,582 5 View

How to analyze LC50 in probit software?

I have mortality chart table but i dont know how to run data in probit software.

09 May 2018 8,693 2 View

Bulk amorphous, but nano crystalline?

My otherwise amorphous material is showing strong XRD peaks when in its nanoparticulate form...cant really guess the reason...need help

02 January 2018 3,668 6 View

Protein precipitation during buffer exchange?

Hi all, I noticed small white precipitates formed during buffer exchange using Vivaspin. I am new to protein biology. I am not sure if the white stuff that I see are protein precipitates or...

29 August 2016 4,279 9 View

Can I use DMINDA for scanning whole genome sequence of a prokaryote to identify transcription factor binding sites?

Hi, I am not very good at computational biology. I am working on a transcriptional repressor protein which is believed to be associated with virulence. I did DNAse 1 footprinting to determine the...

30 July 2016 5,886 3 View

Can any body tell the dosage of nanoparticles for biodistribution?

21 September 2015 7,215 3 View

I need to image mesoporous silica nanoparticles that are in ~100 nm size and do high resolution TEM to look at mesopores. what grids should I use?

Need to image mesoporous silica nanoparticles using the TEM. Also, need high resolution TEM images to see the mesoporous structure. Kindly suggest what kind of grids to use. Thanks, Shatadru

02 March 2021 1,787 2 View

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02 March 2021 3,060 3 View

Do I need to strip the PVDF membrane before staining it with colloidal gold?

Dear Colleagues, After running Western blot on PVDF membrane and detection using ECL, I would like to stain my PVDF with colloidal gold to be able to allign the ECL image with total proteins on...

02 March 2021 7,829 3 View

Discrete Phase model (DPM) particle break-up has particle size limits during particle tracking?

Hello, I am currently working on simulating water droplet partciles in a closed room. When I use uniform particles, without "particle break-up", I can carry out the simulation without any problem....

02 March 2021 3,053 2 View

Can chitosan alone can act as a reducing agent for Cu(0) nanoparticle sythesis?

[Synthesizing Cu nanoparticles without using chemical reductants]

01 March 2021 8,359 1 View

Issues with Permeabilization during Flow Cytometry?

Hello Everyone. Currently I am working to characterize macrophages in the myocardium after ischemia-reperfusion injury in rats. Due to the low total cell number isolated from rat hearts I can...

01 March 2021 3,867 3 View

Which cell line should we use to perform biological dosimetry experiments?

We are preparing some experiments based on irradiating cells under different conditions in order to evaluate the effects in terms of DNA damage, genetic expression, etc. As our project is...

01 March 2021 3,355 3 View

What are the new 2D nanomaterials were used for Silver nanoparticles stabilization?

In the stabilization of AgNPs are vital in current research interest. However, some of the 2D nano-materials like graphene oxide, MoS2, etc... previously used to stabilize it. But still they shown...

01 March 2021 2,207 3 View

What is the state of the drug inside solid lipid nanoparticles (SLNs)?

I am a little confuse with the mechanism of solid lipid nanoparticles (SLNs). The main point of encapsulating drugs into SLNs is because some drugs have low solubility in water. Therefore, SLNs...

01 March 2021 3,703 3 View

How to check the uv-vis absorption of nanoparticle by surface plasmon resonance?

I try to check the uv-vis absorption of Indium nanoparticle. Now I am measuring in solution, can I measure it in the form of a film?

01 March 2021 930 3 View