I see many papers that used different doses of Salmonella Enteritidis in the chicken infection model for the same type of chickens e.g., Ross-308 broiler. It also varies at different ages of the chickens, but I found different doses for the same-aged chickens. The dose varied from 1*10^5 to 1*10^9. So, how can I decide which dose I should try to give a challenge to chickens for my experiment?
Mohammad Ali Poorkhalily
Dear researcher, according to the state of the bird's immune system, the dominant dose of the microbial population in the occurrence of pathogenicity will be different. Also, the bird's immune system is influenced by age. Therefore, in detailed tests, the microbe strain is usually tested with different doses and ages to get the best results.
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