Respected sir/ maam i am preparing nanoparticles niosomes but the buffer i used is precipitated continuously , how i can resolve this issue?
Storage condition = Room temperature
pH=7.4
You made need to find a different buffer. Since niosomes are made from nonionic surfactants, it's possible that the stability that occurs in the absence of the buffer is due to weak electrostatic interaction. If your buffer is isotonic, it could simply be the ionic strength is too high. If you require isotonicity, try using a non-electrolyte to control the osmotic pressure (e.g., dextrose or glycerin).
Respected sir thanks alot for your great cooperation. Actually main is the precipitation of buffer solution itself with in 72 hours at room temperature , how I can prevent from it ?
Please help me
Is there anything else in the buffer? Is it just a solution of potassium phosphate in water? What concentration?
- Badges
- Science topic
- Similar topics
- Engineering
- Electrical Engineering
- Electrodes