Dear friends ,what wonderful question that millions need, ar friends ,here is something about magnesium, ing paper Neutra [1] has pointed out that a limitation in research on magnesium (Mg) is that concepts have been driven by metabolic studies conducted with a handful of subjects. Epidemiologists have certainly played a very small role in recent years, compared with the intense activity by cellular biologists working with a very wide range of animals and other organisms. Neutra went on to indicate that the most important deficiencies in knowledge about Mg are those that relate to public health and he recommended that further research should relate to possible public health actions. There are several important hypotheses relevant to Mg and human health. One of the most important is that tissue Mg is predictive of cardiovascular disease, a low Mg level increasing the risk of a vascular disease event. A second is that supplementary Mg, given in the acute phase of a myocardial infarction, reduces mortality. A third is that long-term dietary Mg supplementation reduces the risk of cardiovascular morbidity and/or mortality. The issue of Mg in acute cardiac infarction has certainly generated a very great interest, and much controversy in recent years. Nevertheless, of the three hypotheses, the first is by far the most relevant to public health, that is, that low Mg levels are a risk factor for cardiovascular disease and death from vascular causes. The other two hypotheses follow from this, the more important relating to prevention by long-term dietary supplementation. In the following, evidence relating to these three hypotheses will be reviewed in the context of a series of questions of increasing importance: 1. How best is body Mg status assessed in epidemiological studies? 2. What are the mechanisms that might be involved in cardiovascular disease? 3. Is there post-mortem evidence that body Mg is relevant to cardiovascular disease? 4. Is there prospective evidence that dietary Mg intake, or body Mg is relevant to vascular disease? 5. Is there experimental evidence that Mg supplementation is beneficial during infarction? 6. Is there experimental evidence that long-term Mg supplementation reduces the future risk of vascular disease events and/or death? 1. How Best is Body Mg Assessed in Epidemiological Studies? Tissue Mg is clearly the measure most likely to be relevant to cardiovascular disease, especially if the tissue is myocardium. It is possible to obtain bone and heart muscle during surgery but samples from groups of subjects likely to be representative of a community can normally be obtained only at postmortem examination. Skeletal muscle on the other hand, can be biopsied during life, but the procedure is unlikely to be acceptable for large epidemiological studies. This also applies to the Mg loading test, even in the one hour shortened form of the test [2]. Only about 0.3 % of body Mg is carried in the serum and the level appears to differ widely between subjects. In the National Health and Nutrition Examination Study (NHANES) the range in serum Mg levels was 0.41 to 1.45 mmol/l [3]. There appears, however, to be little correlation between dietary intake and serum Mg. In Atherosclerosis Risk in Communities (ARIC) study, the correlation coefficient was 0.09 in men and 0.04 in women [4] and in the men in the Caerphilly cohort [5] it was 0.05. Although all these coefficients are statistically significant, they imply that less than one percent of the variation in serum Mg levels can be explained by differences in dietary intakes. This raises the question as to the value of one or other of these variates. Furthermore, Altura [6] has repeatedly and persuasively argued that it is free Mg ions (Mg2+) that are biologically active and that it is these that induce the array of pathophysiological effects. Unfortunately, no epidemiological study to date appears to have used this measure. It can be argued, however, that in relation to issues of public health the most relevant measures relate to dietary intake and estimates of these can be made in large numbers of subjects, representative of defined populations. Estimates of intake can also be made from chemical analyses of duplicate diets provided by selected subjects, and balance studies can be used to estimate requirements. Neither of these types of studies are appropriate for studies based upon large population samples of subjects, but the valuable evidence they give is reviewed elsewhere in this issue (see, Vormann and Anke, this issue). M

• magnesium.pdf232.90 KB

RecommendShare📷Tareq Alasadi

• 11.06
• Wasit University

Answer

Dear Tareq Alasadi,

Magnesium deficiency has been linked to insulin resistance, which is central to the development of type 2 diabetes, research shows.

On the flip side, increasing your intake of magnesium has been shown to possibly lower your risk of developing the chronic disease.

Research suggets consuming 100 milligrams (mg) of magnesium through eating foods rich in the mineral may decrease the risk of diabetes by 15 percent.

I hope I have answered your question.

With Best Wishes,

Samir G. Pandya

Magnesium deficiencyhas been linked to insulin resistance,which is central to the development of type 2 diabetes, research shows.

Magnesium helps regulate blood sugar.

Dear researcher,very good reply ,magnesium is very important in diet,so see these foods

• Fruits (such as bananas, dried apricots, and avocados)
• Nuts (such as almonds and cashews)
• Peas and beans (legumes), seeds.
• Soy products (such as soy flour and tofu)
• Whole grains (such as brown rice and millet)
• Milk.

Dear friend ,thankyou for good reply ,here are some additional points . agnesium is a mineral that is important for normal bone structure in the body. People get magnesium from their diet, but sometimes magnesium supplements are needed if magnesium levels are too low. Dietary intake of magnesium may be low, particularly among women. Magnesium deficiency is also not uncommon among African Americans and the elderly. Low magnesium levels in the body have been linked to diseases such as osteoporosis, high blood pressure, clogged arteries, hereditary heart disease, diabetes, and stroke.

An easy way to remember foods that are good magnesium sources is to think fiber. Foods that are high in fiber are generally high in magnesium. Dietary sources of magnesium include legumes, whole grains, vegetables (especially broccoli, squash, and green leafy vegetables), seeds, and nuts (especially almonds). Other sources include dairy products, meats, chocolate, and coffee. Water with a high mineral content, or "hard" water, is also a source of magnesium.

Magnesium is most commonly used for constipation, as an antacid for heartburn, for low magnesium levels, for pregnancy complications called pre-eclampsia and eclampsia, and for a certain type of irregular heartbeat (torsades de pointes).