Hi ,
can you tell me why Escherichia coli is always used as an experimental Organism? What features does it have to make it suitable for cloning and transformation, bacterial conjugation, protein expression?Why not another bacterium?
Thanks
Michael J. Benedik
The reason is purely history. E. coli was one of the first bacteria where genetic manipulations were worked out and hence it became the most studied organism through the middle and latter part of the 20th century. It is by no means the best organism to use, but is still in use due to the immense literature that exists. Many scientists have (and still do) proposed using other bacteria as "model" organisms but none have replaced E. coli.
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