Regarding to the Functions of the Warburg Effect and tumour microenvironment also enhances disruptions of tissue architecture and immune cell evasion.
Why do oncogenes induce the Warburg Effect cell intrinsically?
Hello, I am working on some single-cell RNA-Seq samples and wondering what the difference between a typical RNA-Seq analysis and single-cell RNA-Seq analysis is? Can we use standard Subread and...
31 December 2019 2,752 3 View
I am studying about relations between warburg effect and cancer evolution and find this question. Why do unicellular organisms and cultured cells use aerobic glycolysis?
31 December 2016 7,052 0 View
Are scientists able to take immortality from cancer cells? what is your comment about this article: Scientists from the Spanish National Cancer Research Centre (CNIO) have discovered a new...
11 December 2015 3,463 4 View
I am wondering to know if it is possible to arrive a point of genetics in the future which we will use immortality feature of cancer cells to modify normal cells to immortal cells?
11 December 2015 1,851 1 View
As a molecular genetics student I would like to ask this great community to advice what is the hot topics in the field of cancer genetics, cancer stem cells, biomarkers and generally the best...
11 December 2015 5,589 0 View
The few cancer cells that are immortal activate telomerase reverse transcriptase (TERT), a part of the telomerase enzyme that rebuilds telomeres so they avoid a telomere crisis. Normally, TERT is...
11 December 2015 4,210 12 View
what is the usage of TEM for studying cancer and Biomarkers? for understanding new aspect of cancer how we can use TEM? there anyone that work with electron microscopy for studying cancer which...
11 December 2014 9,143 0 View
We are already studying DNA and chromatin with different methods (For example using Osmium Ammine for DNA staining) but I want ask if someone also work in this field with the same methods or there...
11 December 2014 4,898 9 View
What are the functions of free calcium in the nucleus and nuclei as a regulation factor for transcription? How does it work? Has somebody done projects related to Ca in the nucleus?
10 November 2014 2,510 7 View
We want to know localization of Calcium in the nucleus or nucleolus or chromatin of HeLa cells and also looking for staining but after staining in the transmission electron microscopy we see lot...
09 October 2014 7,676 7 View
The rate of glucose consumption by the neocortex is reduced by over 80% during anesthesia (Sibson et al. 1998), which disables the synapses (Richards 2002) that are inundated by glial tissue (Engl...
08 August 2024 3,118 0 View
Hello everyone, I have recently started using the microtome device for sectioning of paraffin-embedded mice lung. While I had some success in sectioning and observing proper ribbons, some of my...
06 August 2024 666 4 View
Evolutionary fitness is based on an organism’s ability to adapt rapidly to changing environmental circumstances. Large-bodied mammals have been equipped with large brains (and hence a high...
06 August 2024 4,849 2 View
Larger brains, which typically contain more neurons, store and transfer more information (Tehovnik and Chen 2015), but the precise relationship between number of neurons and information has yet to...
05 August 2024 1,238 2 View
Brain and body mass together are positively correlated with lifespan (Hofman 1993). The duration of neural development is one of the best predictors of brain size, and conception is the best...
05 August 2024 6,247 3 View
I will be with my students collecting seaweed samples in a marine farm and later we will process this tissue for RNA isolation and further sequencing. Does anyone have tips on how to collect the...
04 August 2024 501 2 View
what are the top 3 challenges to the advancement of the field of Radiogenomics in cancer research? is it the availability of easily available low-cost matched imaging and biosamples with clinical...
03 August 2024 5,828 4 View
I heard an explanation about something being a better proton acceptor or lone pair donor but that doesn't make sense. I couldn't explain in in terms of acid-base theory. The hand-waving way I saw...
03 August 2024 9,918 0 View
I am following Hainmueller, Hopkins, and Yamamoto's (2014) paper for my randomized conjoint experimental data analysis. The link to the paper is provided below. I received a comment from the...
02 August 2024 4,406 0 View
All plants are green but some of these plants becomes yellow. I did not found any reason. Please help me to find out the real problem.
01 August 2024 589 4 View