I have read a few studies that have found an increased expression level of 19 genes on the X chromosome associated with slower cognitive decline only in women, suggesting a possible protection from cognitive decline in aging and AD.
You can read the articles in detail.
References:
1. Article Sex-Specific Association of the X Chromosome With Cognitive ...
2. Article Sex and Gender Differences in Neurodegenerative Diseases: Ch...
3. Article Sex and Gender Differences in Neurodegenerative Diseases: Ch...