Hello

Basic Principle of ISET :

ISET methodology is a direct method for CTC/CTM

identification, in which CTCs are isolated by filtration without

use of tumor-associated markers, as a result of their large

size relative to circulating blood leukocytes, and necessitates

a module of filtration and a polycarbonate track-etch-type

membrane with calibrated 8-Mm-diameter cylindrical pores.

ISET uses the following steps: (i) peripheral blood collection

and processing ; (ii) optional enrichment of large

cells by blood filtration ; and (iii) characterization

of large cells on the membrane

Please , read carefully the attachments , i hope help you .

Good luck

Thank you very much, very useful the documentation

Luis