I have some novel protein sequences, i want to know their location. Suggest some online tool for signal peptide identification.
Hi Santos, you may find plenty of bioinformatic tools at http://www.expasy.org/tools/
If you want to focus in signal peptide identification only you may try this one:
SignalP 4.1 Server
SignalP 4.1 server predicts the presence and location of signal peptide cleavage sites in amino acid sequences from different organisms: Gram-positive prokaryotes, Gram-negative prokaryotes, and eukaryotes. The method incorporates a prediction of cleavage sites and a signal peptide/non-signal peptide prediction based on a combination of several artificial neural networks.
Good luck!
Felix
Hi Santosh, Whatever Felix has suggested that is a very good server. But I would suggest you to cross check with other available tools on expasy. I am attaching the link below.
https://www.expasy.org/resources/search/keywords:signal%20peptide
They have Phobius, SecretomeP PSORT and many other.
Other than this PrediSi is a recent tool. I found that very useful. http://nar.oxfordjournals.org/content/32/suppl_2/W375.full
http://www.predisi.de/
Good Luck
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