Which TLR4 agonist is better for vaccinating BALB/c mice with?

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Sandeep Rajput

Go for LPS, Lippopolysacharide

LPS is most potent agonist for TLR4. It will serve your purpose and there are many literature on pubmed.

Mosayeb Rostamian

Thank you Sandeep

Acctually I want to finally test the whole product (Vaccine+ TLR4 Agaonist) on human cells, as you know i could not use LPS on human so is not better to use MPL which is aproved for human use, for all my experiments? If you agree with me the question is remained unanswered!