Hi!
I have several sets (e.g. 100) of essential genes + non-essential ones, all were extracted from a certain database of essential genes for a particular disease under different conditions. How can I compare these sets to check if the results obtained under different conditions (100) are significant?
For instance, set #1 contains 2000 genes containing 100 essential genes (found in the hypothetical database) + 1900 non-essential genes, and so forth.
Thanks in advance
Dear Jochen,
Thanks for your answer; however, I don't understand how to create the 2-by-2 contingency table for these data sets. Each set contains essential vs. non-essential genes, however, the main database (which essential genes are taken from) only contains essential genes. Therefore, each set was originally consisted of a mixture of genes, which this very database was used to identify essential ones.
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