Oveis Jamialahmadi

10 Questions 23 Answers 0 Followers

Questions related from Oveis Jamialahmadi

Repeated N-fold cross validation?

Hi! I am a bit confused with the term of "repeated" in repeated CV. In a typical cross validation problem, let's say 5-fold, the overall process will be repeated 5 times: at each time one subset...

26 November 2016 3,102 5 View

When to use FDR?

I have a problem with the concept of false discovery rate. Assuming I have a panel of 50 anticancer drugs for which their IC50 values are reported for 30 cell lines. On the other hand, I have a...

03 June 2016 8,763 2 View

Where can I find a complete list of oncogenes and TS for NCI-60 cell lines?

I am wondering if such a list/database is available for cancer in general or cell lines in NCI-60. Unfortunately, I could not find such a list from a cursory glance at papers in google scholar;...

27 February 2016 1,237 2 View

Why in BiGG models, each metabolite corresponds to more than one KEGG metabolite?

Metabolites in SBML models in BiGG database contain annotations for providing additional information on other identifiers such as KEGG cpds. However, in some cases for each metabolite there exists...

22 October 2015 3,944 0 View

What is a suitable panel for normal/cancerous liver cell lines?

Hi, I plan to do some gene silencing in HepG2 cell line. However, to draw a profound comparison between normal and cancerous liver (in this case, hepatocellular carcinoma) phenotypes, a normal...

20 September 2015 2,077 5 View

Which parameters affect the choice of a tumor cell line?

There are various cell lines in literature from different cell collections (ATCC, DSMZ, etc.) or personal donations extracted from patients or just a gift from a generous researcher. However, not...

12 September 2015 6,945 6 View

How to extract gene expression and proteomics data from Human Protein Atlas?

I am trying to extract some cell-specific transcriptomic/proteomic data for cancerous tissues from Human Protein Atlas, however, it did not work out. I appreciate any cues in doing so, and if...

15 August 2015 5,353 4 View

What is the effect of Beta-sheets and random coils on refolding yield and protein aggregation?

Is there any publication or research on effect of beta-strand and specially random coils on the propensity of proteins to aggregation and as a result, a reduction in refolding yield? There are...

20 July 2013 1,579 1 View

Remove L-Arginine?

Is there any appropriate way to remove L-arginine from a buffer? I need to measure protein concentration in a buffer containing L-arginine. As L-arginine interacts with bradford buffer (or in 280...

28 May 2013 725 10 View

How can we concentrate small volumes of a protein solution?

Is there any special centrifuge filter or another instrument for the purpose of tiny volumes?

05 May 2013 8,117 15 View