Some proteins or peptides are synthesized non-ribosomally. Do we really need the presence of all 3 RNA molecules in protein synthesis
- How independent do you think non-ribosomal synthesis is from ribosomes. This synthesis is mediated by NRPS, an enzyme. Of course it is normal protein and needs ribosomes and all three RNA.
- Non-ribosomal peptides are mostly made by bacteria or fungi
- Do you/we (as a human) have a choice? as you said, "do we really need......". Do you think it is logical?
rRNA, tRNA, and mRNA are all essential components for ribosomal peptide synthesis.
Nonribosomal peptide synthesis requires a different gene for each type of peptide, and the mRNAs transcribed from those genes are converted into the synthetase enzymes by ribosomal protein synthesis.
Transfer RNAs, or tRNAs, play an integral role in protein synthesis in all life forms. tRNAs contain anticodons (three nucleotides long sequence), which base pair to codons on mRNAs during translation (for eg., UCG base pairs to AGC), and therefore deliver the covalently bound amino acid to the nascent peptide chain. The base pairing to the right codon on the mRNA ensures that the correct amino acid is added to the nascent peptide chain. Therefore, besides facilitating protein synthesis, they also play a role in ensuring the fidelity of protein synthesis.
- Badges
- Science topic
- Similar topics
- Biological Science
- Molecular Biology
- Biomolecules
- Nucleic Acids
- RNA