With the appearance of COVID-19 vaccines on the market, many available choices are there.
Which one is good?
Which one is safest?
Which one is most expensive?
Which one is easiest to store?
How many doses are required?
Other than intramuscular injection, any other forms?
How to check immune response after?
Do we need post-injection blood test?
Do we need annual booster dose?
Do we need new vaccines every year by prediction as if flu vaccines?
Any contraindications?
Any allergy from vaccination?
Do we need to mask after injection?
Currently available COVID-19 vaccines are unable to provide life long immunity against the disease.
Looking forward as a ray of hope to end the pandemic..
Afraid about its side effects.
The mRNA vaccine is expected to be safe and effective. Utilizing a decade old technology which was fast-tracked during this pandemic.
Results of Pfizer and Moderna vaccines are very promising and showing a good safety profile.
I would encourage all to take it as the first step to tackle this pandemic.
Based on the data from the company thay published at NEJM, i would say the efficacy is high about 95%. Short term safety was very good. The common side effect was the fatigue. BUT no body yet on earth can gurantee the long term complication of mRNA based vaccine.
We only know about short term prevention. Though initial results are encouraging with antibody level ….We may have to wait until at least end of 2021 to have a proper idea on long term immunity and adverse effects... And the amount of doses being given in such a short time will result in greater media attention for even rare side effects. With more in number due to large number of doses being administered in a short period.
prevention is better than cure. Boost up your immunity with remedies until WHO approved vaccination.
vaccine will be always safer then first new virus infection in adults - i hope i will take my shot early , only restriction to phase III complete vaccines
Vaccine will be positive step to fight with COVID19. Even then hygeine and social distancing should be maintained. because we don't know how vaccine will protect us from mutated version of virus
In the first week of December, federal authorities announced the start of a large-scale vaccination campaign with Sputnik V. It will start on Saturday, December 5 in Moscow and next week in the regions. The first to be vaccinated will be doctors, teachers and social workers. In Moscow, five thousand people have signed up for vaccination in the first five hours, the mayor's office said.
https://www.bbc.com/russian/news-55185179
CORONAVIRUS VACCINE: WHAT'S HAPPENING IN RUSSIA AND THE WORLD
German pharma company CureVac has started a phase II clinical trial of its candidate vaccine CVnCoV against COVID-19. The company reports that 36,500 people over the age of 18 from Europe and Latin America will take part in the trial. The phase IIb-III study is designated as a randomised, blinded, placebo-controlled, multicentre study. For more information on how vaccine development is progressing globally, as well as vaccination and research in Russia, please see Vademecum's update broadcast.
14 December
- The US Food and Drug Administration (FDA) has announced that it has granted emergency approval for a coronavirus vaccine from Pfizer and BioNTech. The FDA found that the vaccine from Pfizer and BioNTech meets the established criteria for issuing an EUA. Studies have shown that the known and potential benefits outweigh the potential risks, allowing the vaccine to be used by millions of people aged 16 years and older, including healthy individuals.
"FDA's approval of the emergency use of the first COVID-19 vaccine is an important milestone in the fight against this devastating pandemic that has affected so many families in the United States and around the world," said FDA Commissioner Stephen M. Khan.
Singapore Prime Minister Lee Hsien Loong said the city-state has also approved the Pfizer-BioNTech vaccine for emergency use. Delivery of the first doses is expected in late December 2020. The official said a sufficient quantity of the vaccine for Singaporeans should arrive in Q3 2021.
- German pharma company CureVac has started phase II clinical trials of candidate vaccine CVnCoV against COVID-19. The company reports that 36,500 people over the age of 18 from Europe and Latin America will take part in the trial. The phase IIb-III study is designated as a randomised, blinded, placebo-controlled, multicentre study.
It is noted that the trials are conducted in accordance with the ethical principles of the Declaration of Helsinki and the International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use (ICH). A detailed description of the study can be found in the register of international clinical trials Clinicaltrials.gov .
- A survey by the Public Opinion Foundation (FOM) on the attitudes of Russians toward vaccination and the domestic vaccine against COVID-19 found that only 42% of respondents admit to being vaccinated against the coronavirus, 52% rule out such an opportunity, and 6% find it difficult to answer this question.
More than half of those surveyed - 68% - attach importance to where the vaccine is produced (for 53% it is very important and for 16% not so important). When asked if they had a choice of vaccinating with a particular vaccine, 51% would prefer a Russian vaccine, 18% a German vaccine, and 9% an American vaccine.
Overall, some 42% of Russians believe that mass vaccination will be able to stop the pandemic coronavirus, while 33% do not believe so.
Read more: https://vademec.ru/news/2020/09/13/vaktsina-ot-koronavirusa-chto-proiskhodit-v-rossii-i-v-mire/
It is considered an effective step to control the epidemic, but questions about its side effects in the long term?
In my own point of view as a nurse, I am confident and relieved with the availability of vaccines to cure diseases. Before the production of the covid19 vaccine, many other vaccines such as the flu, polio, hepatitis, measles, mumps etc. have been widely used in different health programs in the world, and the efficiency of these vaccines to treat and prevent diseases are proven and tested, contributing to the attainment of maximum health goals of every nation. Through the use of science and technology, we are now equipped with major resources to fight diseases as big as the ones in the history and at the real time of covid19 pandemic.
Dearly respected
Take the vaccine if not contraindicated. No matter which type, the truth is that millions passed due to this dangerous virus. Never wait to see something that may or may not happen, even if some people are affected or not, it is not a guarantee that you will do the same. People differ widely.
Well, over the past two weeks:
Covid killed >150,000 people
Covid vaccines killed = 0 people
Dear Sunny Chi Lik Au,
Yes, there are many questions that we do not know the answer to today as citizen immunization programs are only just beginning in many countries. The production of vaccines recently started in several pharmaceutical companies. The production was preceded by tests. However, citizens pose many questions that still remain unanswered. these responses will emerge in a few months (e.g. on the contribution of the vaccine program to the acquisition of social immunity, on the collective immunity of citizens, and on the ending of the current 2nd and 3rd pandemic waves) and also in about a year (e.g. whether new mutated, more infectious and pathogenic for Covid-19 varieties of the SARS-CoV-2 Coronavirus, whether current vaccines will work against these new varieties of the SARS-CoV-2 Coronavirus, and whether it will be necessary to produce new types of vaccines by pharmaceutical companies). Already, many countries have entered into agreements and / or purchased specific quantities of million doses of vaccines from selected pharmaceutical companies (currently mainly Pfizer and Moderna). In the spring of 2021, vaccines will be available to citizens in some countries from several different pharmaceutical companies. The characteristics of all these vaccine offers from individual pharmaceutical companies are not identical, so the question arises according to which criteria and the scope of published information, citizens will choose which pharmaceutical company to choose vaccine to be vaccinated against the SARS-CoV-2 (Covid-19) coronavirus. Consequently, there is still much to be clarified, and there are still many unanswered questions. These responses should appear as soon as possible to enable effective and efficient improvement of anti-panic risk management and crisis management systems operated by central public safety institutions.
Best wishes,
Happy New Year 2021
Dariusz Prokopowicz
I am skeptical about the efficacy of these rushed vaccines, especially how they will be efficient in tropical Africa and Africa as a whole. No one has told us what the side effects in the future will look like.
I'm confident in the vaccine. Last week I signed up on the waiting list, at the request of my employer (a public institution in the central administration).
these vaccines already aproved by emea, will help to mitigate the severe forms of cov infection - hope they will be soon available for all
The Pfizer-BioNtech vaccine, which started being rolled out in the UK last month, offers up to 95% protection against Covid-19. Vaccination has been shown to prevent severe infection, so even if people do catch the virus, they would be protected from getting seriously ill. https://www.bbc.com/news/uk-wales-55579028
Based on what we know about vaccines for other diseases, experts believe that getting a COVID-19 vaccine may help keep you from getting seriously ill even if you do get COVID-19. https://www.cdc.gov/coronavirus/2019-ncov/vaccines/vaccine-benefits.html#:~:text=Based%20on%20what%20we%20know,get%20COVID%2D19.
Most of the vaccines are roughly 95% effective, according to the companies, meaning that about 5% of people who get the vaccine may still develop symptomatic disease after being exposed. Also, other groups of people, like those who are immunocompromised, may not develop as much immunity. https://abcnews.go.com/Health/lawmakers-tested-positive-covid-19-capitol-riot-vaccinations/story?id=75277616
When the familiar antigens are detected, B-lymphocytes produce antibodies to attack them. Vaccines prevent diseases that can be dangerous, or even deadly. Vaccines greatly reduce the risk of infection by working with the body's natural defenses to safely develop immunity to disease. https://www.cdc.gov/vaccines/hcp/conversations/downloads/vacsafe-understand-color-office.pdf
Currently available COVID-19 vaccines are unable to provide life long immunity against the disease.
None of the currently approved SARS-CoV-2 vaccines will provide life-long immunity to the disease but can only last for 5 months.
The best positive view is to look at the vaccine as a solution to get out of the present crisis. At the same time, vaccine can help in restoring normalcy as far as travel is concerned. This can translate to going back to sports events / meetings / holiday / trade, helping economy to a great deal.
Russia's Sputnik V COVID-19 vaccine appears safe and 91.6% effective.
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(21)00234-8/fulltext
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