Hi, everyone, I recently came across two antifade agents at the same price point—AntiFade Mounting Medium (with DAPI) (Cat. No.: HY-K1047, from MedChemExpress) and AntiFade Reagent (with DAPI).(Cat. No.: HY-K1048, from MedChemExpress). They seem quite similar, but I‘m not sure what the fundamental differences are between them? Has anyone used them before?
The difference between these two anti-fade mounting media lies primarily in their sealing methods and application scenarios:
HY-K1047 (with DAPI) is a self-hardening anti-fade mounting medium, characterized by:
Automatically solidifying after mounting to form a permanent, rigid seal
Eliminating the need for additional sealants (e.g., nail polish) around the coverslip edges
Suitable for long-term sample preservation
HY-K1048, on the other hand, is a conventional anti-fade mounting medium with the following features:
Remains in liquid form, solely providing anti-fade protection
Requires manual sealing (e.g., with nail polish or specialized sealant) after observation
Ideal for temporary observations or experiments requiring repeated coverslip removal
Both reagents are priced the same; the choice should be based on experimental needs: HY-K1047 for long-term storage, HY-K1048 for temporary use.
The answer to this question comes from MedChemExpress (MCE) Technical Support.
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