there are suitable kits and protocols to extract RNA from embedded samples.

Thanks Amilcare Barca,  would You like to guide me which will be suitable for Skin samples, I am working on wound healing model .........

I think this could be good enough for you.

RNeasy FFPE Kit

https://www.qiagen.com/it/products/catalog/sample-technologies/rna-sample-technologies/total-rna/rneasy-ffpe-kit?cmpid=QVenRNA1303RNAwheelEM#productdetails

pay attention to the starting sample weight requested... work accordingly strictly to the manual.

mlk

if you have very few starting material you can use RNA FISH from affymetrix http://www.affymetrix.com/estore/promotions/qgviewrna/index.affx it is more pricy but the result are great and you can see the heterogeneity of the expression of your gene in function of cellular type. you can do 2-3 mRNA in the same time in fluorescence or color based...

Dear All, A lot of thanks for sending me Your valuable suggestion,,,,

Many perfect kits from life technology and Qiagen are available to extract RNA from FFPE, which can be used for varaiety of down stream procedures like Transcriptome analysis, expression studies.