I am try to make the Paal Knorr reaction between 2.5 hexnedione and 6-amino hexanoic acid, my problem is type of solvent to use, because 6-hexaminohexanoic acid is soluble in water but I am not sure if there are another solvents, I am try with glacial acetic acid but is very difficult to remove from the system.
On the other hand, I am try to replicate this reaction in polymers.