How to over come the error in GROMACS simulation (Protein-Ligand) during Add-Ions ?

HI All, "ERROR : No.of Coordinates in Solv.gro and Topol.top not matching" I am trying to run GROMACS simulation for Protein-Ligand complex, and I am facing this issue, and I dont know how to...

31 December 2019 8,943 3 View

How to construct BH plot, Jobs plot for UV absorbance data ?

I have data for UV absorption of anionic sensors. I want to construct BH plot and Jobs plot to find the binding ratio for sensor-ligand complex.

31 December 2016 6,228 4 View

Suggest some Peer Reviewed Journals "Without Processing Fee" ?

Hi Friends, I am searching for some peer reviewed journals, that do not require any processing or publication fee. Can anyone suggest some well known journals. It has to be Indexed in...

04 May 2016 2,899 8 View

How can I identify a Species of a Streptomyces strain?

One of my 16S rRNA gene sequencing resulted in 93% similarity to NCBI database., suggesting it could be a novel or new species., which im not sure yet. For this case, what should i further do...

08 September 2015 7,275 11 View

Does chloroform melt the Eppendorf tube ?

01 February 2015 9,907 9 View

What is the UV range for Magnesium nanoparticle ?

I have been searching for a while now., but I couldn't get any information on the spectrum range for Magnesium nanoparticles. For.eg., Silver Nanoparticle falls between 400 to 500nm in UV...

10 November 2014 6,525 4 View

Does Freezing affect the result of Histopathology analysis?

If a tissue sample is stored in Deep Freezer (-20 C) for a few days, and then thawed to room temperature before Histopathology analysis, will it affect the result?

05 June 2014 5,123 4 View

Can anyone give me a protocol for a biochemical assay for a tissue sample?

I am looking for laboratory biochemical assays for tissue samples to estimate Catalase, Glutathione Peroxidase, Superoxide Dismutase in an animal tissue sample. Alternative to Gel Activity...

05 June 2014 166 12 View

Anyone interested in working on Plasmodium BioInformatics ?

I am looking for a research scholar (PhD student / Professor / JRF) who is interested in working on Plasmodium BioInformatics. I do have a concept to work with and also open to new topics, if you...

04 May 2014 2,249 4 View

Does anyone know where to do 16s RDNA sequencing?

I would prefer the cost be as low as possible, as I can already find 3.5k and 2.8k rupee ones. I am looking for suggestions where to do it a bit cheaper.

03 April 2014 1,469 4 View

Dear all, I was wondering if anyone knows whether MGLtools and Autodock can run on Mac OS?

I have tried to download the 64-bit version of MGLtools however, as many times as I have downloaded and uninstall the programs, an error arises that the app needs to be updated. Thank you.

03 March 2021 5,997 2 View

What is the difference between genotype and haplotype data in the ped format?

Hi everybody In the ped format for genotype, alleles of any SNP are represented by two columns (one for each allele, separated by a space). Is a column sufficient for the haplotype to...

27 February 2021 1,965 1 View

Are there any databases for gene co-expression or expression pattern clustering?

I am currently working on gene clustering based on co-expression pattern in mouse brain. The problem is I do not have some solid way to test my result. Are there any suggestions for databases...

22 February 2021 4,374 3 View

What are the potential shell well and atomic solvation parameters for the boron atom?

I have a protein-ligand docking project. The ligand contains boron atoms that are not detected by Autodock software. To solve this problem, it is necessary to introduce the boron atom to...

19 February 2021 1,236 1 View

Useful architecture for bioinformatics?

Hi Dear researchers In ensemble-based architectural design Which algorithms are more useful for classification? What is the difference between parallel and ensemble architecture? Thanks I am...

08 February 2021 2,727 5 View

How to Remove different version of atom from pdb Crystal Structure for Docking Preparation?

I am new to Docking and MD, and currently try to catch on it. I try one of the webserver for docking, but unfortunately not working. it says " Your PDB contains multiple forms of the same residue...

08 February 2021 7,426 3 View

Electron density difference maps(Fo-Fc): what is the meaning of negative densities (red blobs)?

Dear community, As far as I understand, negative density features point at stuff that is in the model, but not supported by experimental data. However, in many cases (e.g. attached image), when...

06 February 2021 2,847 2 View

Do you have any experience with transfection of EBV immortalized B cells with Lipofectamine?

I know that efficiency of transfection for primary B cells is very low with Lipofectamine. But I did not try that for EBV immortalized B cells. Do you have any experience with transfection of EBV...

05 February 2021 4,159 1 View

Qiime2- No reads passed the filter. How to set the trunc value?

Hi, I am working on some 16S sequencing data, and seems some of them are low quality. I am not sure how to set the trunc value in dada2. qiime dada2 denoise-paired \ --i-demultiplexed-seqs...

30 January 2021 6,213 3 View

Which software to use to statistically analyze Telomere Length_TRF_Southern Blot?

I am trying to measure telomere length in an ant species using the TRF method, which is a Southern blot technique. Currently, I am struggling with analyzing the images and would appreciate any...

29 January 2021 604 3 View