Good day,
I am a student trying to work on Autodock for a project regarding Ligand-DNA interaction so i am quite new to molecular docking. i have followed tutorials and did all the steps recommended for the docking to work with PDBQT files for both the ligand and DNA, but every time i run AutoGrid the window for the process opens for less than 1 second and then shuts down immediately with no output file. i made sure the previous steps were working correctly and to open the ligand and DNA files in their respective input category and the paths for each part in the run window right before the launch have no spaces and are correct. Same problem happens with Autodock.
Does anyone know if there is a fix for this problem?
Thank you in advance.
Uninstall all the docking related files..and also delete their source files from C drive..Then again download and install the software properly...I think the problem will be resolve
This happens in many cases
For testing use can use cmd for docking like:
1. open up cmd and locate the woeking directory
2. do Autogrid- autogrid4.exe -p grid.gpf -l grid.glg
3. After this, initiate docking- autodock4.exe -p dock.dpf -l dock.dlg
4. The output dock.dlg can be vistalized in AutodockTools.
Regards
https://yogeshgaikwad-labhelper.github.io/multidockweb.github.io/index.html
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