I need small particles between 5 and 10 um.What material would be suitable? What encapsulation specific procedures would fit for such small particles? I manage to obtain encapsulation in alginate of both hydrophobic and hydrophilic agents but the particles are to big (240 um).
Try Octenyl Succinic Anhydride (OSA) modified starches which are prepared by incorporation of lipophilic component. These wall materials are most preferred for encapsulation due to its good emulsifying and film forming properties, high oil loading capacities, oxygen barrier properties and low molecular weigh. Because of these activities it is widely used for encapsulation of hydrophobic and hydrophillic active agents. Also, after encapsulation of active agents it will give particles between 5-20 micron most preferably by spray drying technique.
One is spray-drying and another is emulsification-solvent evaporation method based on ionotropic gelation technique, provided high shearing overhead stirrer must be used.
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