This article can be helpful:

https://pubs.rsc.org/en/content/articlehtml/2015/ce/c5ce01014d

Fundamental growth principles of colloidal metal nanoparticles – a new perspective

for chemical reactions , you can use comsol multiphysics

This article can be helpful:

https://pubs.rsc.org/en/content/articlehtml/2015/ce/c5ce01014d

Fundamental growth principles of colloidal metal nanoparticles – a new perspective

For the chemical reaction you can use the general model related Particle size prediction and nano particles to enhance the thermal conductivity and applications.

I recommend Comsol multiphysics