Immunosuppression is the principal method of controlling the disease, and corticosteroids are the cornerstone of therapy. In cases of exacerbation, intravenous pulsed methylprednisolone followed by oral taper may be necessary. Treatment is guided by the clinical response to corticosteroids. If the response is favorable (ie, steady amelioration of symptoms), then the dose may be tapered over several months. Follow-up by a neurologist every 3-6 months to monitor the progress of the disease is important.

Relapses may respond poorly, however, requiring long-term steroid therapy. The prognosis with peripheral neuropathy is more favorable than with central nervous system involvement.

How do you monitor the improvement in the patient - clinical or radiological ???