The bioconcentration factor is referred as a particular concentration of specific chemical inside biological tissues to that of surrounding environment. The bioaccumulation is referred as the chemical concentration of aquatic organism reach a level when it exceeds in water due to uptake of chemicals when it is exposed to chemicals by transport of respiratory surface, dietary absorption and dermal absorption. It is a combination of biomagnification and bioconcentration of chemical under environmental conditions. The biomagnification is a process of increase in chemical concentration with food chain tropic level. The chemical bioaccumulation is referred generally as bioaccumulation factor. The ratio of chemical concentration of aquatic organism to the water concentration that includes dietary uptake is called as bioaccumulation factor.

When the aquatic organism is capable of achieving the level that can exceed water level due to exposure of organism to water but does not include the dietary uptake concentration is referred as bioconcentration. The bioconcentration refers to chemical obtained under normal environmental condition. The chemicals are absorbed by skin or respiratory surface right from water. The chemical bioconcentration extension is referred as bioconcentration factor.

The concentration of chemical in testing substance like fish or aquatic organisms to the chemical concentration in the surrounding environment at steady state condition is bioconcentration factor. The steady state is achieved when organism is exposed to chemicals for an adequate period of time. Thereby the ratio remains constant without any change. The pollutant in aquatic organism to that of pollutant in water can be predicted by bioconcentration factor determination.

Estimation of bioconcentration factor for narcotics shall explain the significant scattering and chaotic collision of compounds. The collision with surface of cell membrane shall represent the geometric characteristics. The structural characteristics effect should be quantified in order to predict the bioconcentration of chemicals.

Thanks a lot. would you please provide me some references regarding the explanation.

I would suggest a review from Arnot & Gobas, 2006. Here you can find a link to the paper http://research.rem.sfu.ca/papers/gobas/A%20Review%20of%20Bioconcentration%20factor%20(BCF)%20and.pdf

why bioconcentration factor of drug is evaluated? is there any relation with toxicity evlaluation?

have a read of these .Hope it helps.

http://research.rem.sfu.ca/papers/gobas/A%20Review%20of%20Bioconcentration%20factor%20(BCF)%20and.pdf

Phytoremediation of Red Mud Deposits Through Natural Succession

Tripti Mishra, Vimal Chandra Pandey, in Phytomanagement of Polluted Sites, 2019