The dose of a substance determines whether something is toxic or not. Carcinogenicity is nearly always studied in models. Not all models are good predictors for the risk in humans.

Conclusion: eat not too much of a single substance and eventually we will all die.

ASPARTAME - Not safest but safer .

Stevia is considered safe in terms of least side effects. 4 mg per kg of body weight is considered safe from an FDA standpoint.

Thanks my dear Prof Srini Vasan for your precise and valuable answer. Rabiul

Aspartame has the same amount of calories as a gram of sugar, but because it is 180 times sweeter than plain sugar, we end up using a lot less to achieve the same sweetness. Aspartame break down into formaldehyde, which is a known carcinogen but more than 100 studies have suggested that it is safe. Currently there are no links between aspartame and cancer. It is unsafe for those people who are affected with rare disorder called phenylketonuria. More of this we can trust on stevia because it is natural.

Dr Tidke

Natural substances can also be carcinogenic. The best known example is aflatoxin.

Dr Kan

you are right sir, but in today’s people have this better option than plain sugar. ofcourse detail study is required to know more. Again stevia is 300 times sweeter than sugar because of this plus point people are consume this alternative in appropriate amount.

OK. Got it. Stevia ... is the best, so far. Thanking you all for your kind contribution. Rabiul

Kindly go through the following RG links.

Article Stevia, Nature’s Zero-Calorie Sustainable Sweetener: A New P...

Article Natural sweeteners: Health benefits of stevia

Article Stevia Rebaudiana: A Potential Boon for Human Health

Thanks Prof Arvind Singh for your nice, definitive and very useful links.

Natural mountain's honey.

For me, I avoid to use sugar right now. Kris Gunnars write article about this issue and it is very interesting ( to read it, Pls, follow this link:

https://www.healthline.com/nutrition/4-healthy-natural-sweeteners

There are four natural sweeteners that are truly healthy

1.Stevia is a very popular low-calorie sweetener.

It’s extracted from the leaves of a plant called Stevia rebaudiana.

2. Erythritol is another low-calorie sweetener.

It’s a sugar alcohol found naturally in certain fruits. However, powdered erythritol available for purchase is most likely made via an industrial process

3.Xylitol is a sugar alcohol with a sweetness similar to sugar.

It contains 2.4 calories per gram, or about two-thirds of the caloric value of sugar.

4.Yacon syrup is another unique sweetener.

It’s harvested from the yacon plant, which grows natively in the Andes in South America.

wish best health for all 🌹

Dear Balqees Al-Musawi

Hassan Izzeddin Sarsak

Hi,

I second the opinions of Prof. Jaydip and Prof. Shekhar. Aspartame is safer than the other alternatives available.

Artificial sweeteners are compounds that offer the sweetness of sugar without the same calories. They are anywhere from 30 to 8,000 times sweeter than sugar and as a result, they have much fewer calories than foods made with table sugar (sucrose). Each gram of table sugar contains 4 calories. Many sugar substitutes have zero calories per gram.

"Artificial sweeteners can serve a definite purpose in weight loss and diabetes control

Thanks Zubaida Falih Al-Zubaidi for your valuable answer, but my inquisition was: what is the safest?

The best and safest artificial sweeteners are erythritol, xylitol, stevia leaf extracts, neotame, and monk fruit extract Md Rabiul Alam