What is the role of H2AX in cancer?

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Autodraw in OSLO software?

Hello everyone, I would like to ask you a very simple question about OSLO software for optical designing. Here I have attached an Autodraw window for an objective lens. Can anyone explain in the...

20 September 2023 6,348 2 View

What strategies are lacking for implementation of sustainable cooling solutions in cities and regions?

20 May 2023 2,620 2 View

Reseach Square is any legal agency of publication? Have any index and Impact Factor?

Why Research Square forces to researcher join the team? Its any useful? some papers online without acceptance in Research Square

05 May 2023 3,730 4 View

Can we calculate energy of any particular molecule?

If we take a protein or peptide, can we calculate energy without excited in higher stage?

31 January 2023 8,450 2 View

How to test laser intensity profile image is a Gaussian distribution ?

I am from Physics, background and doing some experiment using a laser source. Using a collimating lens, I have made the beam as a collimated beam. The intensity distribution of collimated beam is...

11 January 2023 7,347 11 View

How can we extract water soluble compounds during extraction highly polar compound like amino acid?

How can we extract water soluble compounds during liquid extraction but pH of Prduct highly basic up to 13 and product Highly soluble in water?

13 June 2021 5,736 3 View

Many people recovering from COVID-19 have of late been afflicted by black fungus or mucormycosis disease. What can be the exact reason?

Recently in India many people recovering from COVID-19 have of late been afflicted by black fungus or mucormycosis disease. What can be reason? how to diagnosis in early stage?

17 May 2021 6,958 26 View

What is main difference between COVID-19 effected patient fever body temperature and typhoid fever body temperature?

We are writing report on COVID-19 fist, second and third wave in different country of the world.

21 April 2021 4,665 2 View

How to extract the on current and off current of TFET form the output results Vds vs Ids and Vgs vs Ids in silvaco Atlas?

i am trying to know the On current and off current of TFET form its characteristics in silvaco Atlas?

19 April 2020 4,453 1 View

How to add a user defined material with high dielectric value in silvaco atlas ?

procedure to add different high dielectric constant material in the silvaco atlas?

16 January 2020 3,629 5 View

Do I need specific antibodies to stain for a fusion protein?

I am staining some brain sections stored in cryoprotectant that express a Histone H2B- GFP fusion protein that were generated ~10 years ago. I know I need to enhance signal with an anti-GFP...

07 August 2024 5,338 2 View

Why did the authors extrapolate a phenotype that they experimentally proved in one bacterial strain across the whole genus of the organism?

I aim to be as skeptical as possible regarding whether a pair of orthologous genes results in the same phenotype in their different but related bacterial organisms under similar environmental...

05 August 2024 6,787 4 View

Why my colony PCR results of my recombinant bacterial not showing any results?

I am performing ligation of the plasmid and a target gene. The steps I have taken are: 1. Double digestion of the plasmid and target gene 2. Ligation of the plasmid with the target gene 3....

05 August 2024 2,570 3 View

Radiogenomics Cancer Research Challenges?

what are the top 3 challenges to the advancement of the field of Radiogenomics in cancer research? is it the availability of easily available low-cost matched imaging and biosamples with clinical...

03 August 2024 5,828 4 View

What is the role of oxidative stress in toxin-induced carcinogenesis?

What is the role of oxidative stress in toxin-induced carcinogenesis? I am currently researching the impact of environmental toxins on children's health and would greatly appreciate insights from...

02 August 2024 3,174 1 View

What is the acceptable p-value cutoff for GO enrichment analysis ?

I have an RNA-seq data that I have analysed using Limma-voom and have extracted the gene IDs, log2FC and the p-values. At p value < 0.05, I have over 10,000 DEGs, however, when I run the GO...

31 July 2024 225 2 View

Inquiry on Maximum Nucleic Acid Volume for 2.5 mL Liposome Solution?

I am currently working on a project involving liposomes and need to determine the maximum volume of siRNA that can be added to a 2.5 mL liposome solution with a total lipid concentration of 10...

30 July 2024 6,420 1 View

Are these cassettes suitable for expressing PETase mutant in E. coli?

I created two potential gene expression cassettes (constitutive and inducible) for expression of a mutant PETase gene on PeptiCloud using the version tree feature, which allows users to create...

28 July 2024 7,559 1 View

Optimal siRNA Volume for Complexation with Liposomes in a 2.5 mL Solution with 10 mg/mL Lipid Concentration?

How much volume of siRNA can I add to 2.5 mL of liposomes with a total lipid concentration of 10 mg/mL?

27 July 2024 6,920 1 View

If my gene of interest has high GC content can it be problematic in sequencing? What kind of error is expected with GC rich gene sequences??

Gene sequencing related trouble shooting

25 July 2024 4,149 2 View