Iron oxide nanoparticles are coated with modified dextran with COOH group. What is the procedure for determining COOH groups by the acid-base titration method in solution?
Prepare a solution of 0.01 M NaOH in water. Add a certain volume of solution containing nanoparticles with COOH l group. Add two to three drops of phenolphetalein indicator and add additional water to the solution.then titrate with NaOH untill the pale purple color appears. Record the equivalent volume and calculate using N1V1=N2V2. N2 can be related to available COOH groups.
first prepare a solution of 0.01 N NaOH in water carefully. then insert into a beaker a defined volume of the solution containing nanoparticles with cooH functional group. add afew drops of phenolphetalein indicator and add also aditional water as solvent. after that titre the solution via the titrant (0.01 N NaOH) until appearing a purple color of the mixture. finally record the equivalent volume and calculate via N1V1=N2V2. N2 can be related to available COOH groups.
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Miran Beigi
Prepare a solution of 0.01 M NaOH in water. Add a certain volume of solution containing nanoparticles with COOH l group. Add two to three drops of phenolphetalein indicator and add additional water to the solution.then titrate with NaOH untill the pale purple color appears. Record the equivalent volume and calculate using N1V1=N2V2. N2 can be related to available COOH groups.
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