Whether the polysacharides are really effective orally as pharmacological agents beyond their high molecular weight?

Plant based polysaccharides are reported to have a big list of pharmacological activities as evidenced by the scientific literatures. I wonder how is this possible when all of them have molecular...

10 November 2017 5,251 1 View

How to separate hydrolysable tannins using Diaion HP 20?

Which mobile phase will serve better separation of hydrolysable tannins in Diaion HP20? On using water, how to recover the compounds?

11 December 2016 399 0 View

Which is the alternate animal model for type II collagen induced arthritis in DBA/1 mice?

Is there any alternate animal model for type II collagen induced arthritis in DBA/1 mice? DBA/1 mice is not available easily and thus suggestion on any preferred animal model for the study is...

11 December 2016 2,628 2 View

What are the therapeutic targets for GBS- Guillian barre syndrome? Is there any available animal model to study GBS?

Please highlight the molecular targets for GBS with appropriate animal model.

31 December 2015 7,021 0 View

Are there any biochemical kits available for lysosomal enzyme estimation in rat serum samples?

Kindly get me a supplier who can deal with biochemical kits - lysosomal enzymes.

10 November 2014 3,655 3 View

Where can we get DBA/1 mice in south India?

10 November 2014 3,301 1 View

How to avoid plagiarism in research publications?

It is a basic ethic which is to be followed by each and every researcher that others work or words should not be copied in their own publications. But this is not there with each and everyone..So...

09 October 2014 2,392 19 View

More than mere lectures and PPT's, what are the various teaching modes that can be adopted to make the students attentive in the class?

Let it be student or faculty, human brain has got the capacity to be attentive on lectures to a maximum of 45 min continuously. Some techniques has to be adopted if we want to go beyond it, even...

09 October 2014 10,016 4 View

What are the essential minimum requirements to act as a reviewer for research publications?

How do journal editors (high impact journals) choose reviewers for their received articles?

09 October 2014 8,692 18 View

What will be the bioavailability rate of plant polysaccharides?

07 August 2014 9,069 3 View

What is the state of the drug inside solid lipid nanoparticles (SLNs)?

I am a little confuse with the mechanism of solid lipid nanoparticles (SLNs). The main point of encapsulating drugs into SLNs is because some drugs have low solubility in water. Therefore, SLNs...

01 March 2021 3,703 3 View

How does an antibody have full intact antibody + half antibody?

Hello, I was just wondering how does a antibody have full intact antibody + half antibody? Is it because of the drug conjugation?

28 February 2021 1,577 1 View

How do I choose contrasts in SPM8?

I am learning how to use SPM for PET and PET-MR analysis, but I haven't found any great resources that explain how contrasts work. I have a series of PET images where our hypothesis argues that...

24 February 2021 1,534 2 View

Does anyone have any ideas why drug-resistant malaria is increasing in Southeast Asia even when those drugs are no longer used?

When dealing with bacterial toxins, there are three varieties of microbes that develop in your petri dish: toxic, resistant, and susceptible. Initially, there are only toxic and vulnerable...

21 February 2021 6,084 5 View

What is the most prevalent drug related problem in the developed countries?

Detecting the drug related problems is an important step in the pharmaceutical care plan

21 February 2021 5,421 3 View

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19 February 2021 8,647 3 View

Could you please share your experience with me on the type of 96 wells plate for MIC determination: Treated Vs Untreated and Round-Vs Flat-bottomed?

I am working on the MIC determination of various antibacterial agents (both water-soluble and- insoluble) against S. aureus, MRSA, and S. pyogenes. Some guidelines recommend using round-bottomed...

17 February 2021 7,029 3 View

How to improve dissolution of neosome?

I have made neosome from herbal drug. Neosomes are stable. But I face problems in dissolution. I used minimum ratio of 1:1:0.25 ( Drug:span 60: Cholesterol and GMs. Now how can I active better...

17 February 2021 3,584 1 View

How to determine the drug loading and the drug release capacity of a polymer micelle using UV spectroscopy?

Currently, I am working on PLA-PEG copolymer micelle for the drug delivery system. I have seen several papers where some researcher talks to centrifuge the drug-loaded micelle to separate the...

13 February 2021 5,822 7 View

Should the AUC in a concentration-time graph of a subcutaneous implant be roughly the same for poeple?

I have 2 concentration time curves of a subcut drug implant. the first group has a peak around the 50 day mark where as the second group does not. Both groups received the same implant by the same...

10 February 2021 2,305 3 View