We are working with soybean proteins that are subjected to various outside stresses (pH, temp., ionic strength, etc.) and we'd like to know a tool to assess changes in structure.
That would be CD/ORD, visit: http://www.google.com/url?sa=t&rct=j&q=&esrc=s&source=web&cd=3&cad=rja&uact=8&ved=0ahUKEwjwxY2R0q_KAhVGNj4KHYLwBA0QFggwMAI&url=http%3A%2F%2Fiupac.org%2Fpolyedu%2Fpage36%2Fpage19%2Fpage25%2Ffiles%2F5_Circular%2520Dicroism_a.doc&usg=AFQjCNFlhm5uombb0Qi22YXE9PAlbu49iQ
For more specific information you would need protein NMR spectroscopy, visit: https://en.wikipedia.org/wiki/Nuclear_magnetic_resonance_spectroscopy_of_proteins
Changes in sensitivity to digestion by proteases such as trypsin, chymotrypsin, and V8 protease can be used to assess changes in tertiary structure using SDS-PAGE.